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an·ti·bod·y
Audio Help [an-ti-bod-ee] Pronunciation Key
Audio Help [an-ti-bod-ee] Pronunciation Key –noun, plural -bod·ies.
| 1. | any of numerous Y-shaped protein molecules produced by B cells as a primary immune defense, each molecule and its clones having a unique binding site that can combine with the complementary site of a foreign antigen, as on a virus or bacterium, thereby disabling the antigen and signaling other immune defenses. Abbreviation: Ab |
| 2. | antibodies of a particular type collectively. |
| Dictionary.com Unabridged (v 1.1) Based on the Random House Unabridged Dictionary, © Random House, Inc. 2006. |
antibodies
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an·ti·bod·y
Audio Help (ān'tĭ-bŏd'ē) Pronunciation Key
(click for larger image in new window) n. pl. an·ti·bod·ies A Y-shaped protein on the surface of B cells that is secreted into the blood or lymph in response to an antigenic stimulus, such as a bacterium, virus, parasite, or transplanted organ, and that neutralizes the antigen by binding specifically to it; an immunoglobulin. [Translation of German Antikörper : anti-, antagonistic (from Latin anti-, anti-) + Körper, body.] |
| The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2006 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved. |
antibody
Audio Help (ān'tĭ-bŏd'ē) Pronunciation Key
(click for larger image in new window) Any of numerous proteins produced by B lymphocytes in response to the presence of specific foreign antigens, including microorganisms and toxins. Antibodies consist of two pairs of polypeptide chains, called heavy chains and light chains, that are arranged in a Y-shape. The two tips of the Y are the regions that bind to antigens and deactivate them. Also called immunoglobulin. Our Living Language : Like other vertebrates, humans possess an effective immune system that uses antibodies to fight bacteria, viruses, and cancer cells. Antibodies are complex, Y-shaped protein molecules. The immune system's B lymphocytes, which are produced by the bone marrow, develop into plasma cells that can generate a huge variety of antibodies, each one capable of combining with and destroying an antigen, a foreign molecule. Antibodies react to very specific characteristics of different antigens, binding them to the top ends of their Y formation. Once the antibody and antigen combine, the antibodies deactivate the antigen or lead it to macrophages(a kind of white blood cell) that ingest and destroy it. High numbers of a particular antibody may persist for months after an invasion, eventually diminishing. However, the B cells can quickly manufacture more of the same antibody if exposure to the antigen recurs. Vaccines work by "training" B cells to recognize and react quickly to potential disease molecules. |
| The American Heritage® Science Dictionary Copyright © 2002 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved. |
antibodies [(an-ti-bod-eez)]
Proteins in the blood that are produced by the body in response to specific antigens (such as bacteria). (See immune system.)
[Chapter:] Medicine and Health
| The American Heritage® New Dictionary of Cultural Literacy, Third Edition Copyright © 2005 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved. |
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