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1949, coined by its discoverer, Dr. Edward C. Kendall, shortening of chemical name, 17-hydroxy-11 dehydrocorticosterone, ultimately from Latin corticis (genitive of cortex; see cortex). So called because it was obtained from the "cortex" of adrenal glands; originally called Compound E (1936).
cortisone cor·ti·sone (kôr'tĭ-sōn', -zōn')
A naturally occurring corticosteroid that functions primarily in carbohydrate metabolism and is used in the treatment of rheumatoid arthritis, adrenal insufficiency, certain allergies, and gout.