1425–75; late Middle English disesed; compare Anglo-French diseasé. See disease, -ed2

nondiseased, adjective
undiseased, adjective

deceased, diseased.
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a disordered or incorrectly functioning organ, part, structure, or system of the body resulting from the effect of genetic or developmental errors, infection, poisons, nutritional deficiency or imbalance, toxicity, or unfavorable environmental factors; illness; sickness; ailment.
any abnormal condition in a plant that interferes with its vital physiological processes, caused by pathogenic microorganisms, parasites, unfavorable environmental, genetic, or nutritional factors, etc.
any harmful, depraved, or morbid condition, as of the mind or society: His fascination with executions is a disease.
decomposition of a material under special circumstances: tin disease.
verb (used with object), diseased, diseasing.
to affect with disease; make ill.

1300–50; Middle English disese < Anglo-French dese(a)se, disaise; see dis-1, ease

diseasedly, adverb
diseasedness, noun

1. morbidity, complaint, derangement, distemper, indisposition, infirmity, disorder, malady.

1. health. 5. cure.
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Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
disease (dɪˈziːz)
1.  any impairment of normal physiological function affecting all or part of an organism, esp a specific pathological change caused by infection, stress, etc, producing characteristic symptoms; illness or sickness in general
2.  a corresponding condition in plants
3.  any situation or condition likened to this: the disease of materialism
Related: pathological
[C14: from Old French desaise; see dis-1, ease]

diseased (dɪˈziːzd)
having or affected with disease

Collins English Dictionary - Complete & Unabridged 10th Edition
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Word Origin & History

early 14c., "discomfort," from O.Fr. desaise, from des- "without, away" (see dis-) + aise "ease" (see ease). Sense of "sickness, illness" first recorded late 14c.; the word still sometimes was used in its lit. sense early 17c. Related: Diseased.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

disease dis·ease (dĭ-zēz')
A pathological condition of a body part, an organ, or a system resulting from various causes, such as infection, genetic defect, or environmental stress, and characterized by an identifiable group of signs or symptoms.

diseased dis·eased (dĭ-zēzd')

  1. Affected with disease.

  2. Unsound or disordered.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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Example sentences
All your story is managing to do is make people think that adopting a lot of
  diseased cats is somehow going to fix the problem.
It spreads through skin-to-skin contact or when there is a diseased amphibian
  in a shared water source.
Those that remained were diseased or fed the local squirrels.
As you clean out the summer garden, pile everything but diseased material onto
  the compost pile.
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