full of meaning, significance, purpose, or value; purposeful; significant: a meaningful wink; a meaningful choice.

1850–55; meaning + -ful

meaningfully, adverb
meaningfulness, noun

See expressive. Unabridged
Based on the Random House Dictionary, © Random House, Inc. 2014.
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World English Dictionary
meaningful (ˈmiːnɪŋfʊl)
1.  having great meaning or validity
2.  eloquent, expressive: a meaningful silence

Collins English Dictionary - Complete & Unabridged 10th Edition
2009 © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins
Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009
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Word Origin & History

1852, from meaning + -ful.
Online Etymology Dictionary, © 2010 Douglas Harper
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Example sentences
People's screen names are often meaningful to them, even if they are
  inscrutable to others.
It is known for the quality of its programs and for meaningful engagement with
  the communities it serves.
On the spending side, immediate cuts are limited, though more meaningful
  reductions will take effect in years to come.
Visitors have few chances for a meaningful interaction.
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