a prefix appearing in loanwords from Greek, where it meant “over,” usually implying excess or exaggeration (hyperbole ); on this model used, especially as opposed to hypo-, in the formation of compound words (hyperthyroid ).
Compare super-.

Greek, representing hypér over, above; cognate with Latin super (see super-); akin to over

hyper-, hypo-.
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World English Dictionary
1.  above, over, or in excess: hypercritical
2.  (in medicine) denoting an abnormal excess: hyperacidity
3.  indicating that a chemical compound contains a greater than usual amount of an element: hyperoxide
[from Greek huper over]

Collins English Dictionary - Complete & Unabridged 10th Edition
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Word Origin & History

from Gk. hyper (prep. and adv.) "over, beyond, overmuch, above measure." As a word by itself, meaning "overexcited," it is attested from 1942, short for hyperactive.
Online Etymology Dictionary, © 2010 Douglas Harper
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American Heritage
Medical Dictionary

hyper- pref.

  1. Over; above; beyond: hyperflexion.

  2. Excessive; excessively: hyperhydration.

The American Heritage® Stedman's Medical Dictionary
Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.
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American Heritage
Science Dictionary
A prefix that means "excessive" or "excessively," especially in medical terms like hypertension and hyperthyroidism.
The American Heritage® Science Dictionary
Copyright © 2002. Published by Houghton Mifflin. All rights reserved.
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